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GOLGA3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q08378 |
| Reactivity | Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 167 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human GOLGA3/Golgin 160 |
| Epitope Specificity | 951-1050/1498 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasmic and Golgi Apparatus. |
| SUBUNIT | Homodimer. Interacts with GOLGA7. Isoform 1 interacts with GOPC while isoform 3 does not. |
| Post-translational modifications | Cleaved by caspases in apoptotic cells. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The Golgi apparatus consists of a series of stacked, flattened membrane stacks called cisternae that are involved in the transport of lipids and proteins in the secretory pathway and are important for Golgi-microtubule interaction. Golgin 160 is a 1,498 amino acid protein that localizes to both the cytoplasm and to the Golgi apparatus and contains a series of coiled-coil domains. Expressed in a variety of tissues, including heart, liver, testis, kidney, lung and salivary gland, golgin 160 functions as a homodimer that interacts with GOLGA7 and is thought to be involved in maintaining Golgi structure and may play a role in nuclear transport and Golgi apparatus localization. Multiple isoforms of golgin 160 exist due to alternative splicing events. |
| Gene ID | 2802 |
|---|---|
| Other Names | Golgin subfamily A member 3, Golgi complex-associated protein of 170 kDa, GCP170, Golgin-160, GOLGA3 |
| Target/Specificity | Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | GOLGA3 |
|---|---|
| Function | Golgi auto-antigen; probably involved in maintaining Golgi structure. |
| Cellular Location | Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein |
| Tissue Location | Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney |
Research Areas
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$ 385.00
Cat# AP55174
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